Protein Therapeutics Drug Discovery
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Monoclonal Antibodies
system to find them. Other types of MABs attach themselves to immune cells so cells carry on producing cells to attack cancer cells. Trastuzumab and Bevacizumab are examples of MABs that are used for breast and stomach cancer to stop the molecules called growth factor receptors from working properly. So the cancer cell no longer receives the signals it needs to survive. Ibritumomab and Tositumomab are examples of MABs used for non-Hodgkin lymphoma that have radioactive substance attached and delivers the drug to the cancer cells. Clinical trials for hundreds of additional antibody drugs are currently underway for the treatment of various cancers, heart disease, infectious diseases, inflammation, and many other diseases.
Monoclonal antibodies (MABs) are types of treatment that act on processes in cells. This type of treatment or biological therapy is widely used in the fight on cancer. There are already many different MABs available to treat cancer. MABs are designed to recognize and target specific proteins on the surface of cells. In the treatment for cancer for example, each antibody recognizes one particular protein and are made to target different types of cancer. There are three main types of MABs, and they work in different ways. They either trigger the immune system to attack cancer cells, block signals to stop cancer cells from dividing or growing, or carry cancer drugs or radiation to cancer cells. Rituximab and Alemtuzumab are examples of MABs that that are used for leukemia that attach themselves to cancer cells, making them easier for the cells of the immune